In some of these stories characters hook up with the wrong people because they're lonely and needy - and then are disappointed. In other stories characters have dishonest and/or unfaithful partners and have a hard time dealing with it (throw the bum out would be my view - but this may be easier said than done).
One story is about parents coping with a baby who's stricken with cancer. Another is about a woman who was holding a friend's baby when an accident occurs, killing the child; of course the woman blames herself and can hardly go on.
I think my favorite story is about an unhappy spouse who learns to use a gun, then gets to shoot a nutcase who breaks into people's homes to make them sing. For me this was the most satisfying tale.
It's a good book but you'll probably need something light and fun after reading it.