The head of the National Intelligence and Operations Service (NIOS) in New York commissions the assassination of Robert Moreno, a suspected American terrorist doing business in the Bahamas. Moreno is killed by a rifle bullet through his hotel window and his body guard and a journalist are "collateral damage", killed by flying glass. A New York prosecutor, Nance Laurel, believes the head of NIOS has no business ordering murders and plans to prosecute him on a conspiracy charge.
Lincoln Rhyme, a quadriplegic forensic genius, and his partner Amelia Sachs, a New York cop, are asked to help procure evidence for the prosecution. Unfortunately, someone REALLY doesn't want evidence and witnesses found and embarks on a spree of torture, murder, bombing, and theft to eliminate them.
The perp apparently has inside information and always seems to be a step ahead of Lincoln and Amelia (who are a little slow on the uptake here in my opinion, willy nilly using cell phones, etc.). Of course Lincoln and Amelia carry on and unravel a very complex plot with a LOT of surprises (nuff said if you don't want spoilers).
Meanwhile, Amelia's worsening arthritis leads to problems on the job and she fears suspension or worse. The book is a page turner with a horrific chef/murderer bad guy that will make you cringe. Good addition to the Rhyme/Sachs saga.